Quantum Dot-Based Screening Identifies F3 Peptide and Reveals Cell Surface Nucleolin as a Therapeutic Target for Rhabdomyosarcoma

Quantum Dot-Based Screening Identifies F3 Peptide and Reveals Cell Surface Nucleolin as a Therapeutic Target for Rhabdomyosarcoma

Active drug delivery by tumor-targeting peptides is a promising approach to improve existing therapies for rhabdomyosarcoma (RMS), by increasing the therapeutic effect and decreasing the systemic toxicity, e.g., by drug-loaded peptide-targeted nanoparticles. Here, we tested 20 different tumor-target...

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Bibliographic Details
Main Authors: Dzhangar Dzhumashev, Andrea Timpanaro, Safa Ali, Andrea J. De Micheli, Kamel Mamchaoui, Ilaria Cascone, Jochen Rössler, Michele Bernasconi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cancers
Subjects:
active targeting
quantum dots
nucleolin
F3 peptide
aptamer
rhabdomyosarcoma
Online Access:https://www.mdpi.com/2072-6694/14/20/5048

Internet

https://www.mdpi.com/2072-6694/14/20/5048

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