Immunoinformatics Analysis of SARS-CoV-2 ORF1ab Polyproteins to Identify Promiscuous and Highly Conserved T-Cell Epitopes to Formulate Vaccine for Indonesia and the World Population

SARS-CoV-2 and its variants caused the COVID-19 pandemic. Vaccines that target conserved regions of SARS-CoV-2 and stimulate protective T-cell responses are important for reducing symptoms and limiting the infection. Seven cytotoxic (CTL) and five helper T-cells (HTL) epitopes from ORF1ab were ident...

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Bibliographic Details
Main Authors: Marsia Gustiananda, Bobby Prabowo Sulistyo, David Agustriawan, Sita Andarini
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/9/12/1459