Nuclear transmembrane protein 199 promotes immune escapes by up-regulating programmed death ligand 1

Summary: The function of transmembrane protein 199 (TMEM199) in cancer development has rarely been studied thus far. We report the nuclear localization of the TMEM199 protein and further analyzed the truncated fractions that mediate its nuclear localization. Cut&Tag assay globally explores the n...

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Bibliographic Details
Main Authors: Wulin You, Hue Luu, Meili Li, Zhiyu Chen, Fangchao Li, Yanfei Zhang, Mingsheng Cai, Tong-chuan He, Jingjing Li
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224027123