Sestrin 2 levels are associated with emphysematous phenotype of COPD.

Sestrins (Sesns) are a family of highly conserved stress-inducible proteins and various stresses have been shown to strongly up-regulate them. Sestrin 2 (Sesn2) deficiency has been shown to partially suppress pulmonary emphysema. The aim of this study was to evaluate Sesn2 levels in COPD patients an...

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Bibliographic Details
Main Authors: Leonidas Angelakis, Andriana I Papaioannou, Evgenia Papathanasiou, Argiro Mazioti, Maria Kallieri, George Papatheodorou, George Patentalakis, Georgios Hillas, Spyridon Papiris, Nikolaos Koulouris, Stelios Loukides, Petros Bakakos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0273652