Inhibiting Neddylation with MLN4924 Suppresses Growth and Delays Multicellular Development in <i>Dictyostelium discoideum</i>

Neddylation is a post-translational modification that is essential for a variety of cellular processes and is linked to many human diseases including cancer, neurodegeneration, and autoimmune disorders. Neddylation involves the conjugation of the ubiquitin-like modifier neural precursor cell express...

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Bibliographic Details
Main Authors: Robert J. Huber, William D. Kim, Sabateeshan Mathavarajah
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/3/482