Evolution of guanylate binding protein genes shows a remarkable variability within bats (Chiroptera)

BackgroundGBPs (guanylate binding proteins), an evolutionary ancient protein family, play a key role in the host’s innate immune response against bacterial, parasitic and viral infections. In Humans, seven GBP genes have been described (GBP1-7). Despite the interest these proteins have received over...

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Bibliographic Details
Main Authors: Ana Pinheiro, J. Ricardo Borges, João Vasco Côrte-Real, Pedro J. Esteves
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1329098/full