RCC1 functions as a tumor facilitator in clear cell renal cell carcinoma by dysregulating cell cycle, apoptosis, and EZH2 stability

Abstract Background RCC1 functions as a pivotal guanine nucleotide exchange factor and was reported to be involved in mitosis, the assembly of the nuclear envelope, nucleocytoplasmic transport in cell physiological processes. Recent studies reported that RCC1 could regulate immunological pathways an...

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Bibliographic Details
Main Authors: Yunfei Wu, Zhijie Xu, Xiaoyi Chen, Guanghou Fu, Junjie Tian, Baiye Jin
Format: Article
Language:English
Published: Wiley 2023-10-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.6594