Chemogenetic emulation of intraneuronal oxidative stress affects synaptic plasticity

Chemogenetic emulation of intraneuronal oxidative stress affects synaptic plasticity

Oxidative stress, a state of disrupted redox signaling, reactive oxygen species (ROS) overproduction, and oxidative cell damage, accompanies numerous brain pathologies, including aging-related dementia and Alzheimer's disease, the most common neurodegenerative disorder of the elderly population...

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Bibliographic Details
Main Authors: Andrei L. Kalinichenko, David Jappy, Georgy M. Solius, Dmitry I. Maltsev, Yulia A. Bogdanova, Liana F. Mukhametshina, Rostislav A. Sokolov, Aleksandr A. Moshchenko, Vladimir A. Shaydurov, Andrei V. Rozov, Oleg V. Podgorny, Vsevolod V. Belousov
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Redox Biology
Subjects:
Oxidative stress
Synaptic plasticity
Brain aging
Neurodegeneration
Long-term potentiation
Hydrogen peroxide
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723000058

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http://www.sciencedirect.com/science/article/pii/S2213231723000058

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