High Level Antibody Response to Pandemic Influenza H1N1/09 Virus Is Associated With Interferon-Induced Transmembrane Protein-3 rs12252-CC in Young Adults

Background: The C allele of the interferon-induced transmembrane protein-3 (IFITM3) SNP rs12252, a common allele in South East Asia and China, is strongly associated with severe influenza infection. However, despite the high occurrence of rs12252-CC genotype in Chinese population (~25%), severe infl...

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Bibliographic Details
Main Authors: Ling Qin, Dayan Wang, Dongfu Li, Yan Zhao, Yanchun Peng, Dannielle Wellington, Yanchao Dai, Huanqin Sun, Jinping Sun, Guihai Liu, Andrew McMichael, Tao Dong, Yonghong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2018.00134/full