Cigarette Smoke and Morphine Promote Treg Plasticity to Th17 via Enhancing Trained Immunity

CD4<sup>+</sup> regulatory T cells (Tregs) respond to environmental cues to permit or suppress inflammation, and atherosclerosis weakens Treg suppression and promotes plasticity. However, the effects of smoking plus morphine (SM + M) on Treg plasticity remain unknown. To determine whethe...

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Bibliographic Details
Main Authors: Ying Shao, Fatma Saaoud, William Cornwell, Keman Xu, Aaron Kirchhoff, Yifan Lu, Xiaohua Jiang, Hong Wang, Thomas J. Rogers, Xiaofeng Yang
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/18/2810