Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples

Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples

Aberrant methylation is one of the most frequent epigenetic alterations that can contribute to tumor formation. Cell-free DNA can originate from tumor tissue; therefore, the evaluation of methylation markers in cell-free DNA can be a promising method for cancer screening. Our aim was to develop a pa...

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Bibliographic Details
Main Authors: Barbara Kinga Barták, Alexandra Kalmár, Bálint Péterfia, Árpád V. Patai, Orsolya Galamb, Gábor Valcz, Sándor Spisák, Barnabás Wichmann, Zsófia Brigitta Nagy, Kinga Tóth, Zsolt Tulassay, Péter Igaz, Béla Molnár
Format: Article
Language:English
Published: Taylor & Francis Group 2017-09-01
Series:Epigenetics
Subjects:
adenoma
cell-free dna
colorectal cancer
dna methylation
liquid biopsy
plasma
biomarker
Online Access:http://dx.doi.org/10.1080/15592294.2017.1356957

Internet

http://dx.doi.org/10.1080/15592294.2017.1356957

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