Role of Uncoupling Proteins in Cancer

Uncoupling proteins (UCPs) are a family of inner mitochondrial membrane proteins whose function is to allow the re-entry of protons to the mitochondrial matrix, by dissipating the proton gradient and, subsequently, decreasing membrane potential and production of reactive oxygen species (ROS). Due to...

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Bibliographic Details
Main Authors: Adamo Valle, Jordi Oliver, Pilar Roca
Format: Article
Language:English
Published: MDPI AG 2010-04-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/2/2/567/