BAF53A drives colorectal cancer development by regulating DUSP5-mediated ERK phosphorylation

Abstract BAF53A, an important subunit of the SWI/SNF epigenetic chromatin regulatory complex, has been implicated as the driver of diverse cancers. However, the role of BAF53A in colorectal cancer (CRC) remains poorly understood. Here, we examined the expression of BAF53A in CRC samples and observed...

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Bibliographic Details
Main Authors: Ziqing Yang, Dandan Huang, Manqi Meng, Wencong Wang, Junyan Feng, Lekun Fang, Honglei Chen, Shaomin Zou
Format: Article
Language:English
Published: Nature Publishing Group 2022-12-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05499-w