Exploration of metabolic responses towards hypoxia mimetic DMOG in cancer cells by using untargeted metabolomics
Hypoxia is considered as one of the most crucial elements of tumor microenvironment. The hypoxia inducible transcription factors (HIF-1/2) are used by the cancer cells to adapt hypoxic microenvironment through regulating the expression of various target genes, including metabolic enzymes. Dimethylox...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Saudi Journal of Biological Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319562X22003424 |