Effect of troxerutin on the expression of genes regulating mitochondrial biogenesis and microRNA-140 in doxorubicin-induced testicular toxicity

Effect of troxerutin on the expression of genes regulating mitochondrial biogenesis and microRNA-140 in doxorubicin-induced testicular toxicity

Background: Application of doxorubicin (DOX) in cancer patients is limited due to its dose-dependent toxicity to nontarget tissues such as testis and subsequent infertility. Due to limitation of our knowledge about the mechanisms of DOX toxicity in the reproductive system, reduction of DOX-induced t...

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Bibliographic Details
Main Authors: Behnaz Mokhtari, Arezou Abdi, Seyed Zanyar Athari, Hojjatollah Nozad-Charoudeh, Alireza Alihemmati, Reza Badalzadeh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Research in Medical Sciences
Subjects:
doxorubicin
microrna-140
mitochondrial biogenesis
testicular toxicity
troxerutin
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2023;volume=28;issue=1;spage=35;epage=35;aulast=Mokhtari

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http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2023;volume=28;issue=1;spage=35;epage=35;aulast=Mokhtari

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