Hydroxychloroquine Attenuates Acute Inflammation (LPS)-Induced Apoptosis via Inhibiting TRPV1 Channel/ROS Signaling Pathways in Human Monocytes

Hydroxychloroquine Attenuates Acute Inflammation (LPS)-Induced Apoptosis via Inhibiting TRPV1 Channel/ROS Signaling Pathways in Human Monocytes

Acute inflammation (INF) and apoptosis are induced in monocytes by the generation of several factors, including the products of cytosolic oxygen free radicals (cROS) and the excessive influx of Ca<sup>2+</sup> via the stimulation of TRPV1. These are main factors in the etiology of monocy...

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Bibliographic Details
Main Authors: Mustafa Güzel, Orhan Akpınar
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Biology
Subjects:
apoptosis
acute inflammation
cytokines
oxidative stress
TRPV1 channel
Online Access:https://www.mdpi.com/2079-7737/10/10/967

Internet

https://www.mdpi.com/2079-7737/10/10/967

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