Genetics of chloroquine-resistant malaria: a haplotypic view

The development and rapid spread of chloroquine resistance (CQR) in Plasmodium falciparum have triggered the identification of several genetic target(s) in the P. falciparum genome. In particular, mutations in the Pfcrt gene, specifically, K76T and mutations in three other amino acids in the region...

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Hlavní autoři: Gauri Awasthi, Aparup Das
Médium: Článek
Jazyk:English
Vydáno: Fundação Oswaldo Cruz (FIOCRUZ) 2013-12-01
Edice:Memorias do Instituto Oswaldo Cruz
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On-line přístup:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000800947&lng=en&tlng=en