Protein and lipid expansion microscopy with trypsin and tyramide signal amplification for 3D imaging

Abstract Expansion microscopy, whereby the relative positions of biomolecules are physically increased via hydrogel expansion, can be used to reveal ultrafine structures of cells under a conventional microscope. Despite its utility for achieving super-resolution imaging, expansion microscopy suffers...

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Bibliographic Details
Main Authors: Ueh-Ting Tim Wang, Xuejiao Tian, Yae-Huei Liou, Sue-Ping Lee, Hsiao-Tang Hu, Chieh-Han Lu, Po-Ting Lin, Ya-Jen Cheng, Peilin Chen, Bi-Chang Chen
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48959-9