Dynamic profiling of immune microenvironment during anti-PD-1 immunotherapy for head and neck squamous cell carcinoma: the IPRICE study

Dynamic profiling of immune microenvironment during anti-PD-1 immunotherapy for head and neck squamous cell carcinoma: the IPRICE study

Abstract Background Immune checkpoint inhibitors of programmed cell death protein 1 (PD-1) represent a significant breakthrough in treating head and neck squamous cell carcinoma (HNSCC), with long-lasting responses and prolonged survival observed in first- and second-line therapy. However, this is o...

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Bibliographic Details
Main Authors: Carinato Hélène, Ombline Conrad, Carole Pflumio, Christian Borel, Manon Voegelin, Alexandre Bernard, Philippe Schultz, Mihaela-Alina Onea, Alain Jung, Sophie Martin, Mickaël Burgy
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Cancer
Subjects:
Head and neck squamous cell carcinoma
Spatial transcriptomic
Immune response
HNSCC tumour microenvironment
Response biomarker
Online Access:https://doi.org/10.1186/s12885-023-11672-x

Internet

https://doi.org/10.1186/s12885-023-11672-x

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