Type 2 Diabetes Mellitus Facilitates Shift of Adipose-Derived Stem Cells Ex Vivo Differentiation toward Osteogenesis among Patients with Obesity

Type 2 Diabetes Mellitus Facilitates Shift of Adipose-Derived Stem Cells Ex Vivo Differentiation toward Osteogenesis among Patients with Obesity

Objective: Sedentary behavior with overnutrition provokes the development of obesity, insulin resistance, and type 2 diabetes mellitus (T2DM). The main progenitor cells of adipose tissue are adipose-derived stem cells (ADSCs) which can change differentiation, metabolic, and secretory phenotypes unde...

Full description

Bibliographic Details
Main Authors: Margarita Agareva, Iurii Stafeev, Svetlana Michurina, Igor Sklyanik, Ekaterina Shestakova, Elizaveta Ratner, Xiang Hu, Mikhail Menshikov, Marina Shestakova, Yelena Parfyonova
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Life
Subjects:
osteogenesis
adipose-derived stem cells
obesity
insulin resistance
type 2 diabetes
cell senescence
Online Access:https://www.mdpi.com/2075-1729/12/5/688

Internet

https://www.mdpi.com/2075-1729/12/5/688

Similar Items