Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins

The gammaretroviral gag cleavage product, p12, is essential for replication at both early and late stages of the virus life cycle. During the early stage of infection, the viral core is released into the cytoplasm, the viral RNA genome is reversed transcribed to cDNA and this viral DNA is then integ...

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Bibliographic Details
Main Authors: Madushi Wanaguru, Kate N. Bishop
Format: Article
Language:English
Published: Shared Science Publishers OG 2018-07-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/gammaretroviruses-tether-to-mitotic-chromatin-by-directly-binding-nucleosomal-histone-proteins/