Are the results of open randomised controlled trials comparing antipsychotic drugs in schizophrenia biased? Exploratory meta- and subgroup analysis

Abstract A recent meta-epidemiological study did not reveal major differences between the results of blinded and open randomised-controlled trials (RCTs). Fewer patients may consent to double-blind RCTs than to open RCTs, compromising generalisability, making this question very important. However, t...

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Bibliographic Details
Main Authors: Stefan Leucht, Spyridon Siafis, Johannes Schneider-Thoma, Aran Tajika, Josef Priller, John M. Davis, Toshi A. Furukawa
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Schizophrenia
Online Access:https://doi.org/10.1038/s41537-024-00442-8