Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single‐Cell Transcriptomics

Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single‐Cell Transcriptomics

Abstract The increased use of low‐dose computed tomography screening has led to more frequent detection of early stage lung tumors, including minimally invasive adenocarcinoma (MIA). To unravel the intricacies of tumor cells and the immune microenvironment in MIA, this study performs a comprehensive...

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Bibliographic Details
Main Authors: Xin Zhang, Boxuan Liang, Yuji Huang, Hao Meng, Zhiming Li, Jiaxin Du, Lang Zhou, Yizhou Zhong, Bo Wang, Xi Lin, Guangchuang Yu, Xuewei Chen, Weixiang Lu, Zhe‐Sheng Chen, Xingfen Yang, Zhenlie Huang
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Advanced Science
Subjects:
cathepsin B+ tumor‐associated macrophages
minimally invasive adenocarcinoma
senescent CD8+ T cells
single‐cell transcriptomics
tumor progression
Online Access:https://doi.org/10.1002/advs.202303753

Internet

https://doi.org/10.1002/advs.202303753

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