Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor.

Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor.

Despite heterologous expression of epitope-tagged GPCR is widely adopted for functional characterization, there is lacking of systematic analysis of the impact of expression host and epitope tag on GPCR expression. Angiotensin type II (AT2) receptor displays agonist-dependent and -independent activi...

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Bibliographic Details
Main Authors: Lili Jiang, Gladys M K Teng, Elaine Y M Chan, Shannon W N Au, Helen Wise, Susanna S T Lee, Wing-Tai Cheung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3466278?pdf=render

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http://europepmc.org/articles/PMC3466278?pdf=render

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