Prediction of CD8+ Epitopes in Leishmania braziliensis Proteins Using EPIBOT: In Silico Search and In Vivo Validation.

Prediction of CD8+ Epitopes in Leishmania braziliensis Proteins Using EPIBOT: In Silico Search and In Vivo Validation.

Leishmaniasis is caused by intracellular Leishmania parasites that induce a T-cell mediated response associated with recognition of CD4+ and CD8+ T cell Line 1Lineepitopes. Identification of CD8+ antigenic determinants is crucial for vaccine and therapy development. Herein, we developed an open-sour...

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Bibliographic Details
Main Authors: Angelo Duarte, Artur T L Queiroz, Rafael Tosta, Augusto M Carvalho, Carlos Henrique Barbosa, Maria Bellio, Camila I de Oliveira, Manoel Barral-Netto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4407964?pdf=render

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http://europepmc.org/articles/PMC4407964?pdf=render

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