Anticancer properties and enhancement of therapeutic potential of cisplatin by leaf extract of Zanthoxylum armatum DC

Anticancer properties and enhancement of therapeutic potential of cisplatin by leaf extract of Zanthoxylum armatum DC

BACKGROUND: Clinical use of chemotherapeutic drug, cisplatin is limited by its toxicity and drug resistance. Therefore, efforts continue for the discovery of novel combination therapies with cisplatin, to increase efficacy and reduce its toxicity. Here, we screened 16 medicinal plant extracts from N...

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Bibliographic Details
Main Authors: Thangjam Davis Singh, Heikrujam Thoihen Meitei, Adhikarimayum Lakhikumar Sharma, Asem Robinson, Lisam Shanjukumar Singh, Thiyam Ramsing Singh
Format: Article
Language:English
Published: BMC 2015-01-01
Series:Biological Research
Subjects:
Zanthoxylum armatum
Apoptosis
ERK activation
Cisplatin sensitization
DNA damage
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100046&lng=en&tlng=en

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http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100046&lng=en&tlng=en

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