EPCR-PAR1 biased signaling regulates perfusion recovery and neovascularization in peripheral ischemia
Blood clot formation initiates ischemic events, but coagulation roles during postischemic tissue repair are poorly understood. The endothelial protein C receptor (EPCR) regulates coagulation, as well as immune and vascular signaling, by protease activated receptors (PARs). Here, we show that endothe...
Main Authors: | , , , , , , , , , , , , , , |
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格式: | Article |
語言: | English |
出版: |
American Society for Clinical investigation
2022-07-01
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叢編: | JCI Insight |
主題: | |
在線閱讀: | https://doi.org/10.1172/jci.insight.157701 |