Co-transplantation of pancreatic islets and microvascular fragments effectively restores normoglycemia in diabetic mice

Abstract Insufficient revascularization of pancreatic islets is one of the major obstacles impairing the success of islet transplantation. To overcome this problem, we introduce in the present study a straightforward strategy to accelerate the engraftment of isolated islets. For this purpose, we co-...

Full description

Bibliographic Details
Main Authors: Selina Wrublewsky, Andrea Weinzierl, Isabelle Hornung, Leticia Prates-Roma, Michael D. Menger, Matthias W. Laschke, Emmanuel Ampofo
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00262-3