Large-Scale Bioinformatics Analysis of <italic toggle="yes">Bacillus</italic> Genomes Uncovers Conserved Roles of Natural Products in Bacterial Physiology

Large-Scale Bioinformatics Analysis of <italic toggle="yes">Bacillus</italic> Genomes Uncovers Conserved Roles of Natural Products in Bacterial Physiology

ABSTRACT Bacteria possess an amazing capacity to synthesize a diverse range of structurally complex, bioactive natural products known as specialized (or secondary) metabolites. Many of these specialized metabolites are used as clinical therapeutics, while others have important ecological roles in mi...

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Bibliographic Details
Main Authors: Kirk J. Grubbs, Rachel M. Bleich, Kevin C. Santa Maria, Scott E. Allen, Sherif Farag, Elizabeth A. Shank, Albert A. Bowers
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mSystems
Subjects:
Bacillus
bioinformatics
natural products
nonribosomal peptide synthetase
polyketides
secondary metabolism
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00040-17

Internet

https://journals.asm.org/doi/10.1128/mSystems.00040-17

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