RANKL neutralisation prevents osteoclast activation in a human ameloblastoma-bone model

Ameloblastoma is a benign, locally invasive epithelial odontogenic neoplasm of the jaw. Treatment of choice is jaw resection, often resulting in significant morbidity. The aim of this study was to recapitulate ameloblastoma in a completely humanised 3D disease model containing ameloblastoma cells, o...

Full description

Bibliographic Details
Main Authors: Judith Pape, Deniz Bakkalci, Rawiya Al Hosni, Benjamin S Simpson, Kristiina Heikinheimo, Stefano Fedele, Umber Cheema
Format: Article
Language:English
Published: SAGE Publishing 2022-12-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314221140500