Methodical Challenges and a Possible Resolution in the Assessment of Receptor Reserve for Adenosine, an Agonist with Short Half-Life

Methodical Challenges and a Possible Resolution in the Assessment of Receptor Reserve for Adenosine, an Agonist with Short Half-Life

The term receptor reserve, first introduced and used in the traditional receptor theory, is an integrative measure of response-inducing ability of the interaction between an agonist and a receptor system (consisting of a receptor and its downstream signaling). The underlying phenomenon, i.e., stimul...

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Bibliographic Details
Main Authors: Judit Zsuga, Tamas Erdei, Katalin Szabó, Nora Lampe, Csaba Papp, Akos Pinter, Andras Jozsef Szentmiklosi, Bela Juhasz, Zoltán Szilvássy, Rudolf Gesztelyi
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
adenosine
CPA
FSCPX
NBTI
A1 adenosine receptor
receptor reserve
receptorial responsiveness method
RRM
Online Access:http://www.mdpi.com/1420-3049/22/5/839

Internet

http://www.mdpi.com/1420-3049/22/5/839

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