Detection of hypermethylation at H19DMR at amniocentesis in a fetus with overgrowth, distended abdomen and Beckwith-Wiedemann syndrome

Detection of hypermethylation at H19DMR at amniocentesis in a fetus with overgrowth, distended abdomen and Beckwith-Wiedemann syndrome

Objective: We present detection of hypermethylation at H19 differentially methylated region (DMR) at amniocentesis in a fetus with overgrowth, distended abdomen and Beckwith-Wiedemann syndrome (BWS). Case report: A 31-year-old, gravida 2, para 1, woman was referred for genetic counseling at 22 weeks...

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Bibliographic Details
Main Authors: Chih-Ping Chen, Schu-Rern Chern, Chien-Hsing Lin, Chin-Yuan Hsu, Hsiang-Yu Lin, Fang-Tzu Wu, Shin-Wen Chen, Wayseen Wang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Taiwanese Journal of Obstetrics & Gynecology
Subjects:
Beckwith-wiedemann syndrome
H19DMR (IC1) hypermethylation
Methylation test
Overgrowth
Prenatal diagnosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1028455921002655

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http://www.sciencedirect.com/science/article/pii/S1028455921002655

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