RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins.

Metazoan genomes encode hundreds of RNA-binding proteins (RBPs). These proteins regulate post-transcriptional gene expression and have critical roles in numerous cellular processes including mRNA splicing, export, stability and translation. Despite their ubiquity and importance, the binding preferen...

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Bibliographic Details
Main Authors: Hilal Kazan, Debashish Ray, Esther T Chan, Timothy R Hughes, Quaid Morris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2895634?pdf=render