RNAcontext: a new method for learning the sequence and structure binding preferences of RNA-binding proteins.
Metazoan genomes encode hundreds of RNA-binding proteins (RBPs). These proteins regulate post-transcriptional gene expression and have critical roles in numerous cellular processes including mRNA splicing, export, stability and translation. Despite their ubiquity and importance, the binding preferen...
Main Authors: | Hilal Kazan, Debashish Ray, Esther T Chan, Timothy R Hughes, Quaid Morris |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-07-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2895634?pdf=render |
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