OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway

OCT4 induces EMT and promotes ovarian cancer progression by regulating the PI3K/AKT/mTOR pathway

BackgroundOctamer-binding transcription factor 4 (OCT4) is a key stem cell transcription factor involved in the development of various cancers. The role of OCT4 in ovarian cancer (OC) progression and its molecular mechanism are not fully understood.MethodsFirst, immunohistochemistry (IHC) assays of...

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Bibliographic Details
Main Authors: Weiwei Xie, Jun Yu, Yujia Yin, Xiaoqian Zhang, Xiaocui Zheng, Xipeng Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
OCT4
ovarian cancer
proliferation
migration
invasion
AKT
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.876257/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.876257/full

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