Exhausted local lactate accumulation via injectable nanozyme-functionalized hydrogel microsphere for inflammation relief and tissue regeneration

Local lactate accumulation greatly hinders tissue repair and regeneration under ischemic condition. Herein, an injectable microsphere (MS@MCL) for local lactate exhaustion was constructed by grafting manganese dioxide (MnO2) -lactate oxidase (LOX) composite nanozyme on microfluidic hyaluronic acid m...

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Bibliographic Details
Main Authors: Jieliang Shen, Ao Chen, Zhengwei Cai, Zhijie Chen, Ruichao Cao, Zongchao Liu, Yuling Li, Jie Hao
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-06-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21004746