Human placenta-derived mesenchymal stem cells attenuate established hyperoxia-induced lung injury in newborn rats

Background: Hyperoxia increases Sonic hedgehog (Shh) expression in neonatal rat lungs. The effect of mesenchymal stem cells (MSCs) on the hedgehog signaling pathway in hyperoxia-induced lung injury is unknown. This study evaluated whether MSCs could inhibit hedgehog signaling and improve established...

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Bibliographic Details
Main Authors: Hsiu-Chu Chou, Chung-Ming Chen
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957220300905