Targeting malaria parasites with novel derivatives of azithromycin

Targeting malaria parasites with novel derivatives of azithromycin

IntroductionThe spread of artemisinin resistant Plasmodium falciparum parasites is of global concern and highlights the need to identify new antimalarials for future treatments. Azithromycin, a macrolide antibiotic used clinically against malaria, kills parasites via two mechanisms: ‘delayed death’...

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Bibliographic Details
Main Authors: Amy L. Burns, Brad E. Sleebs, Maria Gancheva, Kimberley T. McLean, Ghizal Siddiqui, Henrietta Venter, James G. Beeson, Ryan O’Handley, Darren J. Creek, Shutao Ma, Sonja Frölich, Christopher D. Goodman, Geoffrey I. McFadden, Danny W. Wilson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
malaria
antimalarial
azithromycin
quick-killing
Plasmodium
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1063407/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1063407/full

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