<i>BRCA2</i> Haploinsufficiency in Telomere Maintenance

<i>BRCA2</i> Haploinsufficiency in Telomere Maintenance

Our previous studies showed an association between monoallelic <i>BRCA2</i> germline mutations and dysfunctional telomeres in epithelial mammary cell lines and increased risk of breast cancer diagnosis for women with <i>BRCA2 999del5</i> germline mutation and short telomeres...

Full description

Bibliographic Details
Main Authors: Soffía R. Gunnarsdottir, Hördur Bjarnason, Birna Thorvaldsdottir, Felice Paland, Margrét Steinarsdottir, Jórunn E. Eyfjörd, Sigrídur K. Bödvarsdottir
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Genes
Subjects:
<i>BRCA2</i>
telomere
haploinsufficiency
Fanconi anemia
chromosomal instability
Online Access:https://www.mdpi.com/2073-4425/13/1/83

Internet

https://www.mdpi.com/2073-4425/13/1/83

Similar Items