Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.

Comprehensive dissection of PDGF-PDGFR signaling pathways in PDGFR genetically defined cells.

Despite the growing understanding of pdgf signaling, studies of pdgf function have encountered two major obstacles: the functional redundancy of PDGFRalpha and PDGFRbeta in vitro and their distinct roles in vivo. Here we used wild-type mouse embryonic fibroblasts (MEF), MEF null for either PDGFRalph...

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Bibliographic Details
Main Authors: Erxi Wu, Nathan Palmer, Ze Tian, Annie P Moseman, Michal Galdzicki, Xuetao Wang, Bonnie Berger, Hongbing Zhang, Isaac S Kohane
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2582946?pdf=render

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http://europepmc.org/articles/PMC2582946?pdf=render

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