Theoretical analysis of wake/sleep changes in brain solute transport suggests a flow of interstitial fluid

Abstract Clearance of protein waste products from the brain is accomplished by a combination of advection and diffusion in cerebrospinal fluid (CSF) and interstitial fluid (ISF). In the glymphatic model, there is a flow of ISF in the interstitial space, and both advection and diffusion occur there....

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Bibliographic Details
Main Author: John H. Thomas
Format: Article
Language:English
Published: BMC 2022-04-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-022-00325-z