GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis

GDF11 inhibits abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis

Aims: Abnormal lipid metabolism is involved in the development of osteoarthritis (OA). Growth differentiation factor 11 (GDF11) is crucial in inhibiting the differentiation of bone marrow mesenchymal stem cells into adipocytes. However, whether GDF11 participates in the abnormal adipogenesis of cho...

Full description

Bibliographic Details
Main Authors: Helin Wang, Yuqian Shi, Feng He, Tao Ye, Shibin Yu, Hui Miao, Qian Liu, Mian Zhang
Format: Article
Language:English
Published: The British Editorial Society of Bone & Joint Surgery 2022-07-01
Series:Bone & Joint Research
Subjects:
temporomandibular joint
osteoarthritis
chondrocyte
sumoylation
gdf11
temporomandibular joints
chondrocytes
staining
lipid
cartilage tissue
mesenchymal stem cells
fatty acid binding protein
cartilage degeneration
rats
adiponectin
Online Access:https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.117.BJR-2022-0019.R1

Internet

https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.117.BJR-2022-0019.R1

Similar Items