Glutathione supplementation improves fat graft survival by inhibiting ferroptosis via the SLC7A11/GPX4 axis

Glutathione supplementation improves fat graft survival by inhibiting ferroptosis via the SLC7A11/GPX4 axis

Abstract Background Autologous fat grafting is hampered by unpredictable graft survival, which is potentially regulated by ferroptosis. Glutathione (GSH), a powerful antioxidant used in tissue preservation, has ferroptosis-regulating activity; however, its effects on fat grafts are unclear. This stu...

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Bibliographic Details
Main Authors: Zehua Li, Jinqiang Lu, Zhiqin Dong, Jiaji Liang, Shenghong Li, Wenwen Han, Taixing Cui, Hongwei Liu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose-derived stem cell
Fat graft
Ferroptosis
Glutathione
Lipotransfer
Online Access:https://doi.org/10.1186/s13287-024-03644-0

Internet

https://doi.org/10.1186/s13287-024-03644-0

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