DNA interference by a mesophilic Argonaute protein, CbcAgo [version 2; peer review: 2 approved]

Background: The search for putative enzymes that can facilitate gene editing has recently focused its attention on Argonaute proteins from prokaryotes (pAgos). Though they are structural homologues of human Argonaute protein, which uses RNA guides to interfere with RNA targets, pAgos use ssDNA guide...

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Bibliographic Details
Main Authors: Nieves García-Quintans, Laurie Bowden, José Berenguer, Mario Mencía
Format: Article
Language:English
Published: F1000 Research Ltd 2020-01-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-321/v2