Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells

Scutellarin enhances anti-tumor immune responses by reducing TNFR2-expressing CD4+Foxp3+ regulatory T cells

One characteristic of tumor-associated CD4+Foxp3+ regulatory T cells (Tregs) is the high expression of tumor necrosis factor receptor type II (TNFR2), a receptor that mediates the decisive effect of tumor necrosis factor (TNF) in the activation and expansion of Tregs. There is increasing evidence th...

Full description

Bibliographic Details
Main Authors: Shaokui Chen, Ruixin Li, Yibo Chen, Chon-Kit Chou, Zhexuan Zhang, Yang Yang, Ping Liao, Qingqing Wang, Xin Chen
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
CD4+Foxp3+ regulatory T cells
Tumor necrosis factor
Tumor necrosis factor receptor II
Scutellarin
CpG oligodeoxynucleotide
Cancer immunotherapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222005765

Internet

http://www.sciencedirect.com/science/article/pii/S0753332222005765

Similar Items