Identification of Tumor Antigens and Immune Subtypes for the Development of mRNA Vaccines and Individualized Immunotherapy in Soft Tissue Sarcoma

Identification of Tumor Antigens and Immune Subtypes for the Development of mRNA Vaccines and Individualized Immunotherapy in Soft Tissue Sarcoma

Soft tissue sarcomas (STS) are a rare disease with high recurrence rates and poor prognosis. Missing therapy options together with the high heterogeneity of this tumor type gives impetus to the development of individualized treatment approaches. This study identifies potential tumor antigens for the...

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Bibliographic Details
Main Authors: Changwu Wu, Yingjuan Duan, Siming Gong, Georg Osterhoff, Sonja Kallendrusch, Nikolas Schopow
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cancers
Subjects:
mRNA vaccine
soft tissue sarcoma
immune subtypes
individualized immunotherapy
tumor immune microenvironment
Online Access:https://www.mdpi.com/2072-6694/14/2/448

Internet

https://www.mdpi.com/2072-6694/14/2/448

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