Bacterial microbiome and host inflammatory gene expression in foreskin tissue

The penile epithelial microbiome remains underexplored. We sequenced human RNA and a segment of the bacterial 16S rRNA gene from the foreskin tissue of 144 adolescents from South Africa and Uganda collected during penile circumcision after receipt of 1–2 doses of placebo, emtricitabine + tenofovir d...

Full description

Bibliographic Details
Main Authors: Brandon S. Maust, Stefan Petkov, Carolina Herrera, Colin Feng, Bryan P. Brown, Limakatso Lebina, Daniel Opoka, Andrew Ssemata, Natasha Pillay, Jennifer Serwanga, Portia Seatlholo, Patricia Namubiru, Geoffrey Odoch, Susan Mugaba, Thabiso Seiphetlo, Clive M. Gray, Pontiano Kaleebu, Emily L. Webb, Neil Martinson, Francesca Chiodi, Julie Fox, Heather B. Jaspan
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023093532