MALDI imaging MS reveals candidate lipid markers of polycystic kidney disease[S]

MALDI imaging MS reveals candidate lipid markers of polycystic kidney disease[S]

Autosomal recessive polycystic kidney disease (ARPKD) is a severe, monogenetically inherited kidney and liver disease. PCK rats carrying the orthologous mutant gene serve as a model of human disease, and alterations in lipid profiles in PCK rats suggest that defined subsets of lipids may be useful a...

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Bibliographic Details
Main Authors: Hermelindis Ruh, Theresia Salonikios, Jens Fuchser, Matthias Schwartz, Carsten Sticht, Christina Hochheim, Bernhard Wirnitzer, Norbert Gretz, Carsten Hopf
Format: Article
Language:English
Published: Elsevier 2013-10-01
Series:Journal of Lipid Research
Subjects:
autosomal recessive polycystic kidney disease
imaging mass spectrometry
Fisher discriminant analysis
taurocholic acid
Fourier transform ion cyclotron resonance mass spectrometry
Matrix-assisted laser desorption/ionization
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520353049

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http://www.sciencedirect.com/science/article/pii/S0022227520353049

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