Cytomegalovirus and Epstein–Barr virus co-infected young and middle-aged adults can have an aging-related T-cell phenotype

Abstract Cytomegalovirus (CMV) is known to alter circulating effector memory or re-expressing CD45RA+ (TemRA) T-cell numbers, but whether Epstein–Barr virus (EBV) does the same or this is amplified during a CMV and EBV co-infection is unclear. Immune cell numbers in blood of children and young, midd...

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Bibliographic Details
Main Authors: Marloes I. Hofstee, Alper Cevirgel, Mary-Lène de Zeeuw-Brouwer, Lia de Rond, Fiona van der Klis, Anne-Marie Buisman
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-37502-5