Coupling TOR to the Cell Cycle by the Greatwall–Endosulfine–PP2A-B55 Pathway

Cell growth and division are two processes tightly coupled in proliferating cells. While Target of Rapamycin (TOR) is the master regulator of growth, the cell cycle is dictated by the activity of the cyclin-dependent kinases (CDKs). A long-standing question in cell biology is how these processes may...

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Bibliographic Details
Main Authors: Livia Pérez-Hidalgo, Sergio Moreno
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/7/3/59